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Hyperkalemia in the Hospital

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Presentation on theme: "Hyperkalemia in the Hospital"— Presentation transcript:

1 Hyperkalemia in the Hospital

2 Case Study: Patient Presentation @ 1:20 am

3 Case Study (cont): EKG @ 1:24 am

4 K+ in the ED

5 Hyperkalemia Management in ED: ECG Changes

6 Overview of Temporizing Treatments

7 Case Study (cont): Options @ 2:50 am

8 Hyperkalemia Management in ED: Reassessment of Patient

9 SPS[a]

10 Rapid Correction of Hyperkalemia Reduces Mortality in ED

11 REVEAL-ED

12 REVEAL-ED: Hyperkalemia Treatment Patterns in the ED

13 REVEAL-ED: Recordable Outcomes*

14 REVEAL-ED: K+ Levels From Start of Treatment

15 "Novel" Potassium Binders

16 Treatment of Hyperkalemia in the ED: Pilot Study

17 Results of Hyperkalemia Treatment in ED With Patiromer

18 New Treatments: ZS-9 Crystal Structure

19 ZS-9 Clinical Development Programme

20 Potassium Levels Decrease Within 1 to 4 Hours After First Dose of ZS-9 in Severe Hyperkalemia

21 Existing Studies Suggest Differences in the Onset of Action of Patiromer and ZS-9, Though There Are No Head-to-Head Trials

22 Take-Home Messages

23 Abbreviations

24 Abbreviations (cont)


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