1. Nurse View: Practice Pearls in Advanced Pancreatic Adenocarcinoma

3. Pancreatic Adenocarcinoma

4. Case 1 78-Year-Old Man in Apparent Good Health

5. Case 1 Diagnosis and Staging

6. Case 1 Further Evaluation

7. Disease-Related Adverse Effects and Palliative Management

8. Disease-Related Adverse Effects and Palliative Management (cont)

9. Return to Case 1 Initial Treatment

10. Adverse Effects of FOLFIRINOX and Gemcitabine as First-Line Therapy

11. Management of Adverse Effects of FOLFIRINOX + Gemcitabine + XRT

12. Return to Case 1 Improvement With Chemotherapy Followed by Symptoms of Locally Advanced Disease

13. Treatment Options for Patients With Metastatic Pancreatic Adenocarcinoma

14. Nanoliposomal Irinotecan (MM-398) in Patients Who Failed to Respond to Gemcitabine

17. Treatment Options for Patients With Locally Advanced Metastatic Pancreatic Adenocarcinoma

18. Case 2 48-Year-Old Woman in Apparent Good Health

19. Case 2 Further Evaluation

20. Adverse Effects of nab-Paclitaxel + Gemcitabine Seen in the Clinical Trial

21. Comprehensive Care of Patients With Metastatic Disease

22. Open Communication With Patients

23. Strategies for Symptom Management and Maintaining Quality of Life

24. What Do You Tell Patients About Clinical Trials?

25. Summary

26. Abbreviations