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Busulfan, Fludarabine, and Alemtuzumab As a Reduced Toxicity Regimen for Children with Malignant and Nonmalignant Diseases Improves Engraftment and Graft-versus-

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Presentation on theme: "Busulfan, Fludarabine, and Alemtuzumab As a Reduced Toxicity Regimen for Children with Malignant and Nonmalignant Diseases Improves Engraftment and Graft-versus-"— Presentation transcript:

1 Busulfan, Fludarabine, and Alemtuzumab As a Reduced Toxicity Regimen for Children with Malignant and Nonmalignant Diseases Improves Engraftment and Graft-versus- Host Disease without Delaying Immune Reconstitution  Jason Law, Morton J. Cowan, Christopher C. Dvorak, Lisa Musick, Janel R. Long-Boyle, Lee Ann Baxter-Lowe, Biljana Horn  Biology of Blood and Marrow Transplantation  Volume 18, Issue 11, Pages (November 2012) DOI: /j.bbmt Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Median donor chimerism. Engraftment percentage is the percentage of donor chimerism detected in whole blood (WB), CD3+, CD14/15+, and CD19+ subsets. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Event-free survival. HCT indicates hematopoietic cell transplant. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Overall survival. HCT indicates hematopoietic cell transplant. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

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