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Catherine A. Necessary, BA, David Roffwarg, MD, Darrel Ellis, MD 

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Presentation on theme: "Catherine A. Necessary, BA, David Roffwarg, MD, Darrel Ellis, MD "— Presentation transcript:

1 Reticulated hyperpigmentation following chemotherapy for radiation-induced osteosarcoma 
Catherine A. Necessary, BA, David Roffwarg, MD, Darrel Ellis, MD  Journal of the American Academy of Dermatology  Volume 71, Issue 1, Pages e23-e24 (July 2014) DOI: /j.jaad Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, Drug reaction. Linear and reticulated areas of hyperpigmentation on the abdomen. B, Drug reaction. Hematoxylin and eosin section showing a mildly atrophic epidermis with focal basal vacuolar change. There is dysmaturation of the keratinocytes likely related to chemotherapy effect. Melanin is present within the stratum corneum. Within the dermis a scant infiltrate of lymphocytes surround the superficial vessels and there are scattered melanophages. Journal of the American Academy of Dermatology  , e23-e24DOI: ( /j.jaad ) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions


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