1. Senescence Indicators are Positively Associated with Severity of Osteoarthritis 
C. Haraden, V. Byers Kraus, D. Attarian, R.-M. Laberge, C.-H. Chou 
Osteoarthritis and Cartilage 
Volume 25, (April 2017)
DOI: /j.joca
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2. Fig. 1. Immunohistochemistry was performed to identify and localize senescent cells in human cartilage. pl6 increased with increasing OA lesion severity.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
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3. Fig. 2. a) Table of representative immunohistochemistry of senescence markers in tibial articular cartilage from regions of varying OA severity from the same patient: oLT (near normal), iLT (early/moderate lesions), MT (severe) of tibial plateau articular cartilage from the same patient. Protein expression of all three senescence markers increased with OA severity, b) PAI-1 immunostaining was positive in MT regions. c) Negative control.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
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