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An Autosomal Dominant Thrombocytopenia Gene Maps to Chromosomal Region 10p  Anna Savoia, Maria Del Vecchio, Antonio Totaro, Silverio Perrotta, Giovanni.

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Presentation on theme: "An Autosomal Dominant Thrombocytopenia Gene Maps to Chromosomal Region 10p  Anna Savoia, Maria Del Vecchio, Antonio Totaro, Silverio Perrotta, Giovanni."— Presentation transcript:

1 An Autosomal Dominant Thrombocytopenia Gene Maps to Chromosomal Region 10p 
Anna Savoia, Maria Del Vecchio, Antonio Totaro, Silverio Perrotta, Giovanni Amendola, Arcangela Moretti, Leopoldo Zelante, Achille Iolascon  The American Journal of Human Genetics  Volume 65, Issue 5, Pages (November 1999) DOI: /302637 Copyright © 1999 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Family pedigree with haplotype reconstruction for informative markers on 10p The at-risk haplotype is boxed. The American Journal of Human Genetics  , DOI: ( /302637) Copyright © 1999 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Schematic representation of a partial linkage map of 12 microsatellite markers located on 10p The mapping order and genetic distances (in cM) were obtained from the Whitehead Institute/MIT Genome Sequencing Project. The boldface segment denotes the linked interval determined by haplotype analysis. The American Journal of Human Genetics  , DOI: ( /302637) Copyright © 1999 The American Society of Human Genetics Terms and Conditions


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