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Potassium-channel opener cardioplegia is superior to St
Potassium-channel opener cardioplegia is superior to St. Thomas’ solution in the intact animal A.Mark Jayawant, MD, Edward R. Stephenson, MD, Gregory S. Matte, BS, George A. Prophet, BS, Kathryn F. LaNoue, PhD, James W. Griffith, DVM, Ralph J. Damiano, MD The Annals of Thoracic Surgery Volume 68, Issue 1, Pages (July 1999) DOI: /S (99)
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Fig 1 Effects of (A) St. Thomas’ solution (St. T) and (B) pinacidil cardioplegia (PIN) on left ventricular (LV) myocardial contractility as assessed by preload-recruitable stroke work relationships (PRSW) before (PRE, solid line) and after (POST, broken line) ischemia. Results are expressed as the mean ± the standard error of the mean. (Lw = PRSW x-intercept; Mw = PRSW slope; r = correlation coefficient.) The Annals of Thoracic Surgery , 67-74DOI: ( /S (99) )
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Fig 2 Effects of (A) St. Thomas’ solution (St. T) and (B) pinacidil cardioplegia (PIN) on left ventricular end-diastolic pressure (LVEDP)–dimension relationships before (PRE) and after (POST) ischemia. Results are expressed as the mean ± the standard error of the mean. (α and β = nonlinear regression coefficients of exponential LVEDP–dimension relationship EDP = α × eβ × V [see Data Acquisition and Analysis section for details]; LV = left ventricular; r = correlation coefficient.) The Annals of Thoracic Surgery , 67-74DOI: ( /S (99) )
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Fig 3 Effect of St. Thomas’ solution (St. T) and pinacidil cardioplegia (PIN) on myocardial tissue water prior to ischemia (PRE), after 2 hours of ischemia (ISC) and after reperfusion (POST). Results are expressed as the mean ± the standard error of the mean. One-way repeated-measures analysis of variance was used. The Annals of Thoracic Surgery , 67-74DOI: ( /S (99) )
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