1. Differences in systolic and diastolic BP between patients randomized to atorvastatin or placebo
Time point
Difference in systolic BP
(mm Hg) p
Difference in diastolic BP
Baseline
0.0
0.95
0.87
6 weeks
0.9
0.02
0.6
0.005
6 months
1.1
0.002
0.001
Closeout
0.1
0.82
0.76
Dahlöf B. American Heart Association Scientific Sessions Nov 7-10, 2004; New Orleans, LA.

2. Primary and secondary end points
Valsartan 160 mg
Valsartan
160 mg/
simvastatin 20 mg
Valsartan 160 mg/
simvastatin 80 mg
p vs valsartan 160 mg
Mean change from baseline in mean 24-hour ASBP
(mm Hg)
-9.2
-9.3
-9.6 NS
Mean change from baseline in mean 24-hour ADBP
-5.5
-6.0
LDL (mg/dL)
2.7
-34.8
-47.2
<0.05
CRP (mg/dL)
-0.16
-0.2
-0.7
<0.0023
Rajagopalan S. American Heart Association Scientific Sessions Nov 7-10, 2004; New Orleans, LA.