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Progestogen treatments for cycle management in a sheep model of assisted conception affect the growth patterns, the expression of luteinizing hormone.

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Presentation on theme: "Progestogen treatments for cycle management in a sheep model of assisted conception affect the growth patterns, the expression of luteinizing hormone."— Presentation transcript:

1 Progestogen treatments for cycle management in a sheep model of assisted conception affect the growth patterns, the expression of luteinizing hormone receptors, and the progesterone secretion of induced corpora lutea  Claudia Letelier, M.V.D., Ph.D., Rosa Ana García-Fernández, M.V.D., Ph.D., Ignacio Contreras-Solis, M.V.D., Ph.D., María Angeles Sanchez, M.V.D., Ph.D., Pilar Garcia-Palencia, M.V.D., Ph.D., Belen Sanchez, M.V.D., Ph.D., Antonio Gonzalez-Bulnes, M.V.D., Ph.D., Juana María Flores, M.V.D., Ph.D.  Fertility and Sterility  Volume 93, Issue 4, Pages (March 2010) DOI: /j.fertnstert Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Growth dynamics of corpora lutea in terms of (A) mean individual measurement of the area and (B) total luteal tissue in the ovaries of control sheep (filled circles) and sheep with estrus synchronized with progestogens (red circles). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Plasma progesterone concentrations of control sheep (filled circles) and sheep with estrus synchronized with progestogens (red circles). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Plasma LH concentrations of control sheep (filled circles) and sheep with estrus synchronized with progestogen intravaginal sponges (red circles). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

5 Figure 4 Immunohistochemical location of LH receptor in corpora lutea of in control (left) and progestogen-treated (right) ewes during late diestrus and early pregnancy: (A, B) day 9, (C, D) day 11, (E, F) day 13, (G, H) day 15, (I, J) day 17, and (K, L) day 21. Stain: streptavidin biotin peroxidase complex, hematoxylin counterstained. Magnification ×20. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions


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