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Pheochromocytoma Producing Vasoactive Intestinal Peptide

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Presentation on theme: "Pheochromocytoma Producing Vasoactive Intestinal Peptide"— Presentation transcript:

1 Pheochromocytoma Producing Vasoactive Intestinal Peptide
Stephen L. Smith, MD, A.L. Jackson Slappy, MD, Thomas P. Fox, MD, James S. Scolapio, MD  Mayo Clinic Proceedings  Volume 77, Issue 1, Pages (January 2002) DOI: / Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Cut surface of the adrenal gland shows a 6-cm medullary tumor with central yellow-white necrosis (arrow) of an otherwise red-pink glistening homogeneous tumor, typical of a pheochromocytoma. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Left, Sheets of tumor cells are divided and packaged by a thin fibrovascular stroma (arrows), creating a typical “zellballen” appearance of a paraganglioma (hematoxylineosin, original magnification x100). Right, Higher power examination reveals variably sized nuclei with some chromatin clearing, tiny nucleoli, and occasional multinucleation. Granular cytoplasm is present in all tumor cells (hematoxylineosin, original magnification x400). Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions


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