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Erdheim-Chester Disease: The Effect of Bisphosphonate Treatment—A Case Report  Sibel Eyigör, MD, Yeşim Kirazlı, MD, Ayşenur Memis, MD, Gülçin Başdemir,

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Presentation on theme: "Erdheim-Chester Disease: The Effect of Bisphosphonate Treatment—A Case Report  Sibel Eyigör, MD, Yeşim Kirazlı, MD, Ayşenur Memis, MD, Gülçin Başdemir,"— Presentation transcript:

1 Erdheim-Chester Disease: The Effect of Bisphosphonate Treatment—A Case Report 
Sibel Eyigör, MD, Yeşim Kirazlı, MD, Ayşenur Memis, MD, Gülçin Başdemir, MD  Archives of Physical Medicine and Rehabilitation  Volume 86, Issue 5, Pages (May 2005) DOI: /j.apmr Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

2 Fig 1 Baseline radiographs of the lower legs (anteroposterior [AP] view). Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

3 Fig 2 Bone scan indicating symmetrically increased uptake.
Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

4 Fig 3 Biopsy of the tibia showed foamy lipid-loaded histiocytes, local inflammatory reaction, giant cells, and osteosclerosis with medullary fibrosis (hematoxylin and eosin stain, ×10). Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

5 Fig 4 One year after baseline radiographs of the tibia (AP view). The lytic lesions in the right tibia enlarged and the number of the lytic lesions in the left tibia increased. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

6 Fig 5 Eighteen months after baseline radiographs of the tibia (AP view). There was no significant difference compared with the radiographs from the first year. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

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