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Ch 27: Female Reproductive System

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1 Ch 27: Female Reproductive System
All organs are internal and closely associated Primary reproductive organs: ? Secondary reproductive organs: ? Female repro system must produce gametes AND maintain developing embryo Medical ppt Fig 27-11

2 Ovaries Suspended by ovarian ligament & suspensory ligament Functions:
Ova production Hormone production

3 Oogenesis (= ovum production)
takes place inside ovarian follicles in ovaries as part of ovarian cycle Oogonia (= stem cells) complete mitotic divisions before birth At birth: ~ 2 mio primary oocytes At puberty: ~ 400,000 primary oocytes 40 years later: 0 (even though only ~ 500 used)  Atresia

4 Tertiary (Graafian follicle)
Oogensis Ovarian cycles start at puberty under influence of ___ Primordial follicle Primary follicle Secondary follicle Tertiary (Graafian follicle) Each month some proceed Few proceed Few proceed Fig 27-12

5 Primordial Follicle or Egg Nests
Present at birth (simple squamous layer) in cortex

6 Follicles enlarge in response to FSH and produce estrogens
Primary Follicle Follicles enlarge in response to FSH and produce estrogens Follicle cells Oocytes

7 Secondary Follicle Few relative to number of primary follicles
Produce follicular fluid Rapid enlargement = Clear glycoprotein layer

8 Tertiary or Graafian Follicle
Spans entire width of cortex First meiotic division being completed: 1oocyte divides into one 2 oocyte and one polar body

9 Oogenesis Happens in tertiary follicle Ovulation
Suspended in prophase I Happens in tertiary follicle Ovulation Stops in Metaphase II

10 Ovulation Oocyte and follicular cells shed into abdominal cavity then
Empty follicle forms corpus luteum which produces progesterone Corpus luteum degenerates and becomes corpus albicans GnRH increases under low estrogen and progesterone levels

11 Uterine Tube = Fallopian tube = oviduct = salpinx Two muscular tubes
infundibulum with fimbriae Ampulla (place of fertilization) Isthmus intramural portion Tubal ligation Fig 27-14

12 Uterine Tube Histology
Ciliated and non-ciliated simple columnar epithelium Ciliary movement and periodic peristaltic contractions move ova Secretion of nutrient substances

13 The Uterus Uterine wall ~ 1.5 cm Blood supply made up of Endometrium,
Myometrium, Incomplete perimetrium Blood supply Uterine arteries from internal iliac Ovarian arteries from abdominal aorta (inferior to renal arteries) Fig 27-16

14 Histology of Endometrium
Functional zone – deciduum, sheds during menses menstruation - flow sheds functionalis layer of endometrium proliferative phase - under influence of estrogen basal cells proliferate secretory phase - progesterone maintains functionalis Basilar zone – permanent layer, deep to functionalis Fig 27-16

15 Functions of Uterus Protection of embryo/fetus Nutritional support
Waste removal Ejection of fetus at birth

16 Cervix and Vagina Cervix attaches to vagina at ~ 90° angle
Fornix – pocket surrounding uterine cervix (surgical access to pelvic cavity; location of birth control device) Vagina – fibro-muscular organ serving as receptacle for intercourse passageway for menstrual products birth canal Fig 27-20b

17 The Mammary Gland Modified sweat gland
Overlaying the ____________ muscle 15-20 separate lobes separated by suspensory ligaments; each lobe contains several secretory lobules Lactiferous ducts leaving lobules; converge into lactiferous sinuses Milk stored in lactiferous sinus until released at tip of nipple Fig 27-21

18 Lymphatic Drainage of Mammary Glands . . .
. . . is of considerable clinical importance, why ?? The End Medical ppt


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