1. Figure 2 Nonmalignant tissue can be spared from radiation
from charged particles owing to the physical properties of these particles
Figure 2 | Nonmalignant tissue can be spared from radiation from charged particles owing to the physical properties of these particles. The treatment plan shown represents a hypofractionated planning target volume dose prescription of Gy to be administered in five fractions to a patient with prostate cancer, with a simultaneous integrated boost to the prostate gland of 40 Gy. a | 4-field ProBeam (Varian Medical Systems, Palo Alto, California, USA) proton plan delivered as intensity modulated proton therapy. b | TrueBeam (Varian Medical Systems) photon plan delivered using two nonplanar volumetric arcs (X-ray-based volumetric arc therapy). Both plans delivered the same target dose, but the integral dose delivered was much lower with protons than with X-rays, and the rectum, the main organ at risk with this treatment, was largely spared from radiation. The plan shown in panel b was designed by Anthony Magliari (Varian) and awarded the top scoring in the 2016 American Association of Medical Dosimetrists and Radiosurgery Society Plan Study. Image courtesy of Dr Anthony Magliari.
Image courtesy of Dr Anthony Magliari.
Durante, M. et al. (2017) Charged-particle therapy in cancer: clinical uses and future perspectives
Nat. Rev. Clin. Oncol. doi: /nrclinonc