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Phylogenetic tree of the human class Frizzled receptors FZD1–10 and SMO created with the ClustalW2 software (ver ; using multiple sequence alignment of FZD1–10 and SMO as shown in the Supplemental material. Phylogenetic tree of the human class Frizzled receptors FZD1–10 and SMO created with the ClustalW2 software (ver ; using multiple sequence alignment of FZD1–10 and SMO as shown in the Supplemental material. Default settings were used. Output format: phylip. Tree type: dist UniProtKB/Swiss-Prot accession numbers used for aligment; see Table 2. Gunnar Schulte Pharmacol Rev 2010;62: Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics
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