1. Prophylactic Magnesium Does Not Prevent Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis 
Richard C. Cook, MD, MS, Michael H. Yamashita, MDCM, MPH, Mark Kearns, MD, Krishnan Ramanathan, MB, ChB, Ken Gin, MD, Karin H. Humphries, DSc 
The Annals of Thoracic Surgery 
Volume 95, Issue 2, Pages (February 2013)
DOI: /j.athoracsur
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Flow diagram to illustrate identification, selection, and exclusion of trials used in the primary meta-analysis.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Forest plot of the random-effects meta-analysis of 21 studies of magnesium (Mg) for the prevention of atrial fibrillation after cardiac surgery. Point estimates, 95% confidence intervals (CI), and study weights are provided for each study. (ID = identifier; OR = odds ratio.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

4. Fig 3
(A) Funnel plot of the 21 studies included in the primary meta-analysis of magnesium for the prevention of atrial fibrillation after cardiac surgery. The precision of each study (standard error of the log odds ratio [OR]) is plotted against each study's effect estimate (OR). (B) Egger plot for the occurrence of atrial fibrillation. Egger's linear regression line, plotted on the Galbraith radial plot. Standard normal deviate (SND) is the odds ratio of each study divided by its standard error. The standard normal deviate is regressed against precision, which is the inverse of the standard error for each study. (CI = confidence interval.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

5. Fig 4
(A) Dose-response curve for total dose of magnesium given. Log (odds ratio [OR]) is plotted against the total dose of magnesium administered in each study. Slope of the line describes the dose-response relationship. (B) Dose-response curve for duration of magnesium therapy. Log (OR) is plotted against the duration of time magnesium was administered in each study. Slope of the line describes the dose-response relationship.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

6. Fig 5
Forest plot of the five high-quality randomized, controlled trials. Model is a random-effects model with odds ratio (OR) point estimates, 95% confidence intervals (CI), and study weights for each study. The “diamond” provides the summary odds ratio for the model. (ID = identifier; Mg = magnesium.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

7. Fig 6
Forest plot of the random-effects model displaying the effect of magnesium on stroke (as defined by the study authors; n = 3 studies). Odds ratio (OR) point estimates, 95% confidence intervals (CI), and study weights are provided for each study. The “diamond” provides the summary odds ratio for the model. (ID = identifier; Mg = magnesium.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

8. Fig 7
Forest plot of the random-effects model displaying the effect of magnesium on mortality (30-day or in-hospital, as defined by the study authors; n = 9 studies). Odds ratio (OR) point estimates, 95% confidence intervals (CI), and study weights are provided for each study. The “diamond” provides the summary odds ratio for the model. (ID = identifier; Mg = magnesium.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

9. Fig 8
Forest plot of the weighted mean difference (WMD) for length of stay (n = 9 studies). The “diamond” is the summary estimate from the random-effects model of the mean different length of stay associated with magnesium use. (CI = confidence interval; ID = identifier; Mg = magnesium.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions