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Metabolic Phenotyping in Health and Disease

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Presentation on theme: "Metabolic Phenotyping in Health and Disease"— Presentation transcript:

1 Metabolic Phenotyping in Health and Disease
Elaine Holmes, Ian D. Wilson, Jeremy K. Nicholson  Cell  Volume 134, Issue 5, Pages (September 2008) DOI: /j.cell Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Interactions between Genes and the Environment and Their Effects on Health Metabolic phenotypes (metabotypes) can be measured by profiling small molecules (<1 kDa) in biofluids (usually urine or blood) by spectroscopic techniques such as NMR. Metabolic phenotypes are influenced by intrinsic and environmental factors that determine health status and disease risk of an individual or group. Measuring and modeling the profile of all metabolites (metabolome) in an individual may provide insights into disease risk factors and etiology, information that could be used for personalized medicine. Cell  , DOI: ( /j.cell ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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