1. A Pause to Splice Molecular Cell
Pia K. Andersen, Torben Heick Jensen 
Molecular Cell 
Volume 40, Issue 4, Pages (November 2010)
DOI: /j.molcel
Copyright © 2010 Elsevier Inc. Terms and Conditions

2. Figure 1 RNAPII Pausing-Assisted mRNA Processing
RNAPII pausing during transcription initiation allows for nascent RNA capping by the Cet1p, Abd1p, and Ceg1p capping factors, of which the two latter bind the RNAPII CTD. RNAPII pausing after the pA site allows for RNA 3′ end formation by the CPF and CFIA complexes. The latter includes the CTD-binding factor Pcf11p. It is now shown that RNAPII pausing near the 3′ splice site (3′SS) may allow for cotranscriptional splicing. Red signs (II) on the gene indicate RNAPII pause sites. U1/U2, U1 and U2 snRNPs that are recruited to 5′SS and 3′SS, respectively; EF, export factor. See the main text for more detail.
Molecular Cell  , DOI: ( /j.molcel )
Copyright © 2010 Elsevier Inc. Terms and Conditions