1. Potential clinical actionability.
Potential clinical actionability. Tumor types are shown by decreasing overall frequency of actionability. Actionability was defined by the union of three knowledge bases: My Cancer Genome ( OncoKB ( and the Personalized Cancer Therapy knowledge base ( For each tumor sample, the highest level of actionability of any variant was considered. Only tumor types with 100 or more samples were included in this analysis.
The AACR Project GENIE Consortium Cancer Discov 2017;7:
©2017 by American Association for Cancer Research