1. Days after cell inoculation Days after cell inoculation
Supplementary Fig. 3 A B C
SW-480/OR
SW-480/OR
SW-480/OR
Naïve
Mimic NC
miR-34a mimic
Naïve
Mimic NC
miR-34a mimic b a a a a c a a a
Relative expression
(miR-34a/U6) b
Cell survival (%)
Apoptosis 405nm) c b b b b a a b a a a
Naïve
Mimic NC
miR-34a mimic
Oxaliplatin (μM)
Oxaliplatin (μM) D E F
SW-480/OR
SW-480
SW-480
Naïve
Mimic NC
miR-34a mimic
Naïve
Inhibitor NC
miR-34a inhibitor a a a a
Relative expression
(miR-34a/U6) a a b b d
Cell survival (%)
Tumor volume (mm3) b c c ** * *
Naïve
Inhibitor NC
miR-34a inhibitor
Oxaliplatin (μM)
Days after cell inoculation G
SW-480 H
SW-480
Naïve
Inhibitor NC
miR-34a inhibitor
Naïve
Inhibitor NC
miR-34a inhibitor c * c **
Apoptosis 405nm)
Tumor volume (mm3) b b a d a a a
Oxaliplatin (μM)
Days after cell inoculation