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Hypoestrogenic “inactive phases” at the start of the menstrual cycle: changes with age and reproductive stage, and relationship to follicular depletion Rebecca J. Ferrell, Ph.D., Germán Rodríguez, Ph.D., Darryl Holman, Ph.D., Kathleen O'Connor, Ph.D., James W. Wood, Ph.D., Maxine Weinstein, Ph.D. Fertility and Sterility Volume 98, Issue 5, Pages e3 (November 2012) DOI: /j.fertnstert Copyright © Terms and Conditions
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Figure 1 Six-month profiles of estrone-3-glucuronide (E1G) and menstrual bleeds for two women. (A) age 47 years, perimenopausal. The long menstrual cycle in the center of the profile begins with an inactive phase of approximately 50 days in length. (B) age 41 years, late premenopausal, with several short inactive phases. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © Terms and Conditions
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Figure 2 Box plots showing the distribution of inactive phase durations (lengths) in days, by age and by reproductive stage, for an average woman. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © Terms and Conditions
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Figure 3 Probability of remaining in an inactive phase by inactive phase duration (length) in days, by age and reproductive stage, for an average woman. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © Terms and Conditions
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Figure 4 The rate (hazard, h) at which women transition from the inactive phase to the late follicular phase, by day of inactive phase (t), by age and reproductive stage, for an average woman. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © Terms and Conditions
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Supplemental Figure 1 Distribution of inactive phase durations (lengths) in days, by age and reproductive stage, for an average woman. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © Terms and Conditions
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