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Volume 72, Issue 4, Pages (October 2017)

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Presentation on theme: "Volume 72, Issue 4, Pages (October 2017)"— Presentation transcript:

1 Volume 72, Issue 4, Pages 534-541 (October 2017)
Quantifying the Transition from Active Surveillance to Watchful Waiting Among Men with Very Low-risk Prostate Cancer  Mieke Van Hemelrijck, Hans Garmo, Lars Lindhagen, Ola Bratt, Pär Stattin, Jan Adolfsson  European Urology  Volume 72, Issue 4, Pages (October 2017) DOI: /j.eururo Copyright © 2016 European Association of Urology Terms and Conditions

2 Fig. 1 State transition model defining transitions (arrows) between states (circles): active surveillance (AS) to curative treatment (radical prostatectomy/radiotherapy, RP/RT), death, AS failure, or watchful waiting (WW) and androgen deprivation therapy (ADT). Red circles represent transient stages and orange circles represent absorbing states. The light orange circles represent additional information gathered to facilitate the estimation of transition probabilities (biopsy and Charlson comorbidity index [CCI]). European Urology  , DOI: ( /j.eururo ) Copyright © 2016 European Association of Urology Terms and Conditions

3 Fig. 2 Proportion of men on active surveillance (AS) who remained on AS, failed AS, changed to watchful waiting (WW) or curative therapy (CT), or died as the first event. All men presented with Charlson comorbidity index of 0 at the time of prostate cancer diagnosis. European Urology  , DOI: ( /j.eururo ) Copyright © 2016 European Association of Urology Terms and Conditions

4 Fig. 3 Estimated number of men who remained on active surveillance (AS) or changed to watchful waiting (WW) over a period of 40 yr for all ages combined and for age groups 52–57 yr, 58–62 yr, 63–67 yr, and 68–72 yr. Estimation included an annual inflow of 1000 newly diagnosed men with very low-risk prostate cancer in each stratum. European Urology  , DOI: ( /j.eururo ) Copyright © 2016 European Association of Urology Terms and Conditions


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