1. National Institue of Infectious Diseases
Intermediate Uveitis in HTLV-1
André Luiz Land Curi
National Institue of Infectious Diseases
INI/IPEC- FIOCRUZ
BRAZIL

2. Ocular History 35 year-old female from Rio de Janeiro
Blurred vision in both eyes for 1 week
Blood transfusion in
HTLV-1 infection known since 2002 with
positive serology

3. At Presentation – 12/2006 VA: 20/60 RE 20/200 LE
Anterior chamber +1/+4 cells, +1/+4 flare,
fine corneal precipitates
cells in the anterior vitreous
vitreous haze +2/+4 OD, +3/+4 OS
retinal vasculitis OU
FLA : Disc and vascular leakage in mid periphery in both eyes

5. Treatment Pulse Methylprednisolone for 3 days Oral Prednisone 60mg/d
Ciclosporine 250mg/d
Prednisone tapering: flare-ups, control with increasing dosage again

6. Last Visit – 12/2013 VA : 20/25 OU no anterior segment inflammation
no signs of vasculitis
vitreous haze +1 OU
Prednisone 5 mg/d with ciclosporin 2x100mg/day

7. Conclusion
HTLV-1 should be included in the differencial diagnosis of intermediate uveitis especially in endemic regions
in special cases immunosuppressive therapy may be needed