2. Case Study 56-year-old Presents With 1 Year of Worsening Dyspnea

3. WHO Clinical Classification of PH Dana Point 2008

4. CTEPH

5. Acute PE Natural History

6. Acute PE Natural History

7. Resolution of Acute PE

10. Chronic Thromboembolic PH

11. Cumulative Incidence of CTEPH*

12. What Are the Risk Factors for Symptomatic CTEPH?

13. CTEPH Physical Findings

14. Index of Suspicion for CTEPH

15. Diagnostic Algorithm in PAH A Disease of Exclusion

16. Is CTEPH Present?

17. Case VQ Scan

18. CT imaging

21. PA Sarcoma

22. What Is the Role of Right Heart Catheterization in CTEPH Evaluation?

23. CTEPH Angiographic Findings

24. Case Intimal Irregularities, Cutoffs

25. Abrupt Vessel Narrowing

26. Therapeutic Algorithm for CTEPH

27. PTE

28. Case PTE Specimen

29. UCSD Outcomes of 2700 Procedures

30. Medical Therapy of CTEPH

31. Emerging Therapy Riociguat

32. CHEST-1 Study Design and Patients

33. Study Schematic

34. Primary Baseline Characteristics

35. Primary End Point 6MWD

36. Adverse Events > 10%

37. CTEPH Treatment Switching From Off-label PAH Treatments to Riociguat

38. Conclusions

39. Abbreviations

40. Abbreviations (cont)

41. Abbreviations (cont)

42. References

43. References (cont)

44. References (cont)