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WASP and WAVE Team Up at the Leading Edge

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Presentation on theme: "WASP and WAVE Team Up at the Leading Edge"— Presentation transcript:

1 WASP and WAVE Team Up at the Leading Edge
Nicolas Molinie, Alexis Gautreau  Developmental Cell  Volume 39, Issue 2, Pages (October 2016) DOI: /j.devcel Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Dual Signaling to the Arp2/3 Complex in Neuroblast Migration
The transmembrane receptor MIG-13 transduces the signal for anterior migration of the right Q cell in the C. elegans embryo. MIG-13 directly interacts with ABL-1 and SEM-5/Grb2, which in turn activate the actin nucleation-promoting factors WAVE and WASP, respectively. At the leading edge of migrating Q cells, distinct foci are formed by WAVE and WASP, with little overlap. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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