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Efficacy of the Long-Acting Repeatable Formulation of the Somatostatin Analogue Octreotide in Postoperative Dumping  Joris Arts, Philip Caenepeel, Raf.

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Presentation on theme: "Efficacy of the Long-Acting Repeatable Formulation of the Somatostatin Analogue Octreotide in Postoperative Dumping  Joris Arts, Philip Caenepeel, Raf."— Presentation transcript:

1 Efficacy of the Long-Acting Repeatable Formulation of the Somatostatin Analogue Octreotide in Postoperative Dumping  Joris Arts, Philip Caenepeel, Raf Bisschops, Dominiek Dewulf, Lieselot Holvoet, Hubert Piessevaux, Stefan Bourgeois, Daniel Sifrim, Jozef Janssens, Jan Tack  Clinical Gastroenterology and Hepatology  Volume 7, Issue 4, Pages (April 2009) DOI: /j.cgh Copyright © 2009 AGA Institute Terms and Conditions

2 Figure 1 Outline of the study protocol. OTE, overall treatment efficacy evaluation. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

3 Figure 2 OGTT at baseline and during treatment with octreotide SC or octreotide LAR IM. (A) Influence on glycemia levels. (B) Influence on pulse rate. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

4 Figure 3 Increase in hematocrit levels at 30 minutes during OGTT at baseline and during treatment with octreotide SC or octreotide LAR IM in 29 postoperative dumping patients. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

5 Figure 4 Total, early, and late dumping severity at baseline and during treatment with octreotide SC or octreotide LAR IM in 29 postoperative dumping patients. *P < .05 compared with baseline. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

6 Figure 5 Quality of life (SF-36) at baseline and during treatment with octreotide LAR in 29 postoperative dumping patients. *P < .05 compared with baseline. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions


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