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Exposure to Nitrofurantoin During Early Pregnancy and Congenital Malformations: A Systematic Review and Meta-Analysis  Ori Goldberg, MD, MPH, Myla Moretti,

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Presentation on theme: "Exposure to Nitrofurantoin During Early Pregnancy and Congenital Malformations: A Systematic Review and Meta-Analysis  Ori Goldberg, MD, MPH, Myla Moretti,"— Presentation transcript:

1 Exposure to Nitrofurantoin During Early Pregnancy and Congenital Malformations: A Systematic Review and Meta-Analysis  Ori Goldberg, MD, MPH, Myla Moretti, MSc, Amalia Levy, PHD, MPH, Gideon Koren, MD  Journal of Obstetrics and Gynaecology Canada   Volume 37, Issue 2, Pages (February 2015) DOI: /S (15) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

2 Figure 1 Search flow chart
Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

3 Figure 2 Major malformations: meta-analysis and forest plot (cohort studies) Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

4 Figure 3 Major malformations: meta-analysis and forest plot (case–control studies) Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

5 Figure 4 Cardiovascular malformations: meta-analysis and forest plot
Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

6 Figure 5 Oral clefts: meta-analysis and forest plot
Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

7 Figure 6 Left hypoplastic heart syndrome: meta-analysis and forest plot Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

8 Figure 7 Craniosynostosis: meta-analysis and forest plot
Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

9 Figure 8 Funnel plot of papers included in meta-analysis
Journal of Obstetrics and Gynaecology Canada   , DOI: ( /S (15) ) Copyright © 2015 Society of Obstetricians and Gynaecologists of Canada Terms and Conditions

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