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Lack of TERT promoter mutations in melanomas with extensive regression

Published byEsa Heikkinen Modified over 6 years ago

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Presentation on theme: "Lack of TERT promoter mutations in melanomas with extensive regression"— Presentation transcript:

1 Lack of TERT promoter mutations in melanomas with extensive regression
Blanca de Unamuno Bustos, MD, Rosa Murria Estal, MSc, Gema Pérez Simó, BSc, Vicente Oliver Martínez, MD, PhD, Margarita Llavador Ros, MD, Sarai Palanca Suela, PhD, Rafael Botella Estrada, MD, PhD  Journal of the American Academy of Dermatology  Volume 74, Issue 3, Pages (March 2016) DOI: /j.jaad Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Association of TERT promoter mutation status and clinicopathologic features. TERT promoter mutations are associated with sex, location, histological subtype, Breslow thickness, ulceration, regression, and mitosis. P values were derived from χ2-test and considered statistically significant if <.05. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Distribution of TERT promoter mutations according to regression. TERT promoter mutations were significantly associated with melanomas without regression. None of the melanomas with extensive regression harbored recurrent mutations. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

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