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Optic neuritis: A mechanistic view
Erik V. Burton, Benjamin M. Greenberg, Elliot M. Frohman Pathophysiology Volume 18, Issue 1, Pages (February 2011) DOI: /j.pathophys Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions
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Fig. 1 Axial (A) and coronal (B) T1 weighted gadolinium enhanced MR images of acute left optic neuritis (arrows). Pathophysiology , 81-92DOI: ( /j.pathophys ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions
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Fig. 2 Fundus appearance of eyes following left optic neuritis in a subject with multiple sclerosis. To the left side of the illustrations we see the normal retina and optic disc of the unaffected right eye and the corresponding nerve fiber layer pattern corresponding to an average retinal nerve fiber layer (RNFL) thickness of 106.4μm. To the right side of the illustration we see the affected eye with optic disc pallor most prominent to the temporal segment and the corresponding nerve fiber layer pattern of thinning corresponding to an average RNFL thickness of 60.9μm with arrows indicating the thinning associated with the temporal pallor. These changes had associated abnormalities in visual function including decreased high contrast visual acuity and low-contrast visual acuity. Pathophysiology , 81-92DOI: ( /j.pathophys ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions
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Fig. 3 High-resolution OCT image of normal human macula. NFL, nerve fiber layer; IPL, inner plexiform layer; OPL, outer plexiform layer; RPE, retinal pigment epithelium; ONL, outer nuclear layer; INL, inner nuclear layer; IS, inner segment; OS, outer segment; ELM, external limiting membrane; GCL, ganglion cell layer. Pathophysiology , 81-92DOI: ( /j.pathophys ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions
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