1. Prospective Study of Motor, Sensory, Psychologic, and Autonomic Functions in Patients With Irritable Bowel Syndrome 
Michael Camilleri, Sanna McKinzie, Irene Busciglio, Phillip A. Low, Seth Sweetser, Duane Burton, Kari Baxter, Michael Ryks, Alan R. Zinsmeister 
Clinical Gastroenterology and Hepatology 
Volume 6, Issue 7, Pages e5 (July 2008)
DOI: /j.cgh
Copyright © 2008 AGA Institute Terms and Conditions

2. Figure 1
SCL-90 mean T scores. Note there are statistically significant differences in anxiety, depression, somatization, general severity index (gsi), and positive symptom total (pst).
Clinical Gastroenterology and Hepatology 2008 6, e5DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

3. Figure 2
Comparison of colonic GC at 24 and 48 hours in healthy controls and IBS patients with different types of bowel dysfunction. #P = .078; *P < .05; **P = .056.
Clinical Gastroenterology and Hepatology 2008 6, e5DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

4. Figure 3
Percentage of participants in each group reaching threshold for first sensation, gas, urgency, and pain in response to step-wise increase in intraballoon pressure; note the significant overlap and lack of any significant differences in any group or any sensation relative to controls.
Clinical Gastroenterology and Hepatology 2008 6, e5DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

5. Figure 4
Sensory ratings of participants in each group for urgency and pain in response to random-order, phasic increase in intraballoon pressure; note the significant overlap for the sensation of pain and the lower sensory ratings for urgency in IBS-C (P = .04 vs healthy controls).
Clinical Gastroenterology and Hepatology 2008 6, e5DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

6. Supplementary Figure
Overlap of abnormal transit and increased sensation in patients with IBS.
Clinical Gastroenterology and Hepatology 2008 6, e5DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions