1. Myometrial response to neurotropic and musculotropic spasmolytic drugs in an extracorporeal perfusion model of swine uteri 
J. Künzel, K. Geisler, I. Hoffmann, A. Müller, M.W. Beckmann, R. Dittrich 
Reproductive BioMedicine Online 
Volume 23, Issue 1, Pages (July 2011)
DOI: /j.rbmo
Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions

2. Figure 1
The experimental model, showing catheter placement in the swine uterus. 1=position of the distal microchip of the intrauterine placed catheter in the corpus uteri; 2=position of the proximal microchip of the intrauterine placed catheter in the isthmus uteri; 3=arterial catheter placed in the A. uterina; 4=ovary.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
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3. Figure 2
Differences in pressure (ΔP) and areas under the curve (ΔAUC) after drug administration in the corpus and isthmus in the various dilution series (1–5 on X-axis represent increasing concentrations, as described for each drug in Materials and methods). (A) ΔP 5min after drug administration in the uterine body. (B) ΔP 5min after drug administration in the isthmus. (C) ΔAUC 5min after drug administration in the uterine body. (D) ΔAUC 5min after drug administration in the isthmus. (E) ΔP 10min after drug administration in the uterine body. (F) ΔP 10min after drug administration in the isthmus. (G) ΔAUC 10min after drug administration in the uterine body. (H) ΔAUC 10min after drug administration in the isthmus. Significant values are shown as absolute figures; P-values are given in the text. Denaverine was only analysed for the 10-min interval. Yellow=butylscopolamine; green=atropine; grey=denaverine (E–H); blue=pethidine; red=celandine; turquoise=metamizole. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this paper.)
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
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4. Figure 3
Representative curve showing the effect of 0.2mg/ml denaverine (Spasmalgan) on uterine pressure. Blue=IUP1; pink=IUP2. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this paper.)
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions

5. Figure 4
Change in pressure with different dosages of celandine 1min after drug administration. An initial increase in pressure was observed for celandine at all dosages; all of the values were significant. P-values are given in the text. Blue=IUP1; pink=IUP2. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this paper.)
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
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6. Figure 5
Intrauterine pressure curve after administration of 1μmol carbachol and 10mg/ml butylscopolamine. The effect of carbachol was initially blocked by butylscopolamine; a second course of administration showed no effect of butylscopolamine after carbachol administration. Blue=IUP1; pink=IUP2. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this paper.)
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
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