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Constructive Remodeling of CorMatrix Extracellular Matrix After Aortic Root Repair in a 90-Year-Old Woman  Frank N. Slachman, MD  The Annals of Thoracic.

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Presentation on theme: "Constructive Remodeling of CorMatrix Extracellular Matrix After Aortic Root Repair in a 90-Year-Old Woman  Frank N. Slachman, MD  The Annals of Thoracic."— Presentation transcript:

1 Constructive Remodeling of CorMatrix Extracellular Matrix After Aortic Root Repair in a 90-Year-Old Woman  Frank N. Slachman, MD  The Annals of Thoracic Surgery  Volume 97, Issue 5, Pages e129-e131 (May 2014) DOI: /j.athoracsur Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Aortic root after explantation. Dashed line delineates the junction between the native aorta and the implanted extracellular matrix patch used for aortic root enlargement. The Annals of Thoracic Surgery  , e129-e131DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Native aorta (Movat pentachrome, scanned at ×10). Solid double arrow, native aorta; solid arrow, neointima; hollow arrow, aortotomy site and suture hole. The Annals of Thoracic Surgery  , e129-e131DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Extracellular matrix patch histology. (A) Movat pentachrome (scanned at ×10). Double arrow, span of extracellular matrix patch (yellow profile); arrow, neointima covering the patch; C, calcified plaque; arrowheads, intima erosion with surface thrombosis; P, polyester rings. (B) Smooth muscle actin (SMA) stain (scanned at ×10). Double arrows, patch showing SMA-positive cellular integration; long arrow, patch adventitia; short arrow, mature fibromuscular neointima; P, polyester. (C) Movat pentachrome (scanned at ×10). Double arrows, patch; arrow, mature fibromuscular neointima; P, polyester. (D) von Willebrand factor (wVF) (scanned at ×10). Arrows, vWF-positive neovascularization along the adventitial side of the patch; double arrow, recellularized patch. (E) Hematoxylin and eosin (scanned at ×10). Double arrow, thickness of patch; arrow, slight inflammation along the patch adventitia. The Annals of Thoracic Surgery  , e129-e131DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions


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