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AID for Innate Immunity to Retroviral Transformation

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Presentation on theme: "AID for Innate Immunity to Retroviral Transformation"— Presentation transcript:

1 AID for Innate Immunity to Retroviral Transformation
Mark S. Schlissel, Tracy C. Kuo  Immunity  Volume 24, Issue 6, Pages (June 2006) DOI: /j.immuni Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Cytidine Deaminase Activities in Animal Cells
Cytidine deaminases (CDAs), long known to be involved in nucleotide salvage pathways, have more recently been found to play key roles in gene expression, anti-viral immunity, and immunoglobulin gene diversification (SHM, somatic hypermutation; CSR, class-switch recombination). Vif is an HIV gene product which interferes with APOBEC3 activity. Immunity  , DOI: ( /j.immuni ) Copyright © 2006 Elsevier Inc. Terms and Conditions

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