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Pegylated interferons

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Presentation on theme: "Pegylated interferons"— Presentation transcript:

1 Pegylated interferons
Umaprasanna S Karnam, MD, K.Rajender Reddy, MD  Clinics in Liver Disease  Volume 7, Issue 1, Pages (February 2003) DOI: /S (02)

2 Fig. 1 Chemical structures of some representative polyethylene glycol molecules. [MPEG, monomethoxypoly (ethylene glycol)]. Clinics in Liver Disease 2003 7, DOI: ( /S (02) )

3 Fig. 2 Effects of pegylation on half-life and antiviral activity. As the molecular weight of the attached PEG moiety increases, the antiviral activity decreases, but the serum half-life increases. Clinics in Liver Disease 2003 7, DOI: ( /S (02) )


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