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Factors That Affect Risk for Pancreatic Disease in the General Population: A Systematic Review and Meta-analysis of Prospective Cohort Studies  Ammar.

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Presentation on theme: "Factors That Affect Risk for Pancreatic Disease in the General Population: A Systematic Review and Meta-analysis of Prospective Cohort Studies  Ammar."— Presentation transcript:

1 Factors That Affect Risk for Pancreatic Disease in the General Population: A Systematic Review and Meta-analysis of Prospective Cohort Studies  Ammar Alsamarrai, Stephanie L.M. Das, John A. Windsor, Maxim S. Petrov  Clinical Gastroenterology and Hepatology  Volume 12, Issue 10, Pages e5 (October 2014) DOI: /j.cgh Copyright © 2014 AGA Institute Terms and Conditions

2 Figure 1 Study selection process. *Two articles investigated both acute and chronic pancreatitis. Three additional studies on pancreatic cancer identified from manual search of article references. #Acute pancreatitis: case-control study, 21; retrospective study, 14; secondary or tertiary centers, 8; non-population representative cohort, 8; non-original article, 4; database recruitment, 3. Chronic pancreatitis: secondary or tertiary centers, 44; experimental study, 14; retrospective study, 7; cross-sectional study, 2; single-gender study, 1. Pancreatic cancer: secondary or tertiary centers, 131; non-population representative cohort, 96; retrospective study, 95; database recruitment, 89; other non-observational study, 56; randomized control trial, 22; non-original article, 19; interventional studies, 14; single-gender study, 36; non-PC specific study, 3. SR, systematic review. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

3 Figure 2 (A) Association of tobacco use with risk of developing acute pancreatitis, chronic pancreatitis, and pancreatic cancer. (B) Risk of developing pancreatic diseases stratified by smoking status. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

4 Figure 3 (A) Association of high BMI with risk of developing acute pancreatitis and pancreatic cancer. (B) Risk of developing pancreatic diseases stratified by BMI. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

5 Figure 4 (A) Association of alcohol use with risk of developing acute pancreatitis, chronic pancreatitis, and pancreatic cancer. (B) Risk of developing pancreatic diseases stratified by amount of alcohol consumption. Clinical Gastroenterology and Hepatology  , e5DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions


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