1. Proposals for the Identification and Prioritisation of Candidate Priority Substances under the next Review
Dean Leverett
Graham Merrington

2. Overall Approach Second Stage Two Stages First Stage
Primarily based on procedures applied in last Review
But also accounting for the outputs of last review
First Stage
Re-evaluation of outputs of last Review
Ensures outputs of last review are utilised to the maximum extent
Identifies ‘high risk’ candidates without need for ‘re-prioritisation’
Second Stage
Monitoring and Modelling-based Ranking Exercises considering;
New candidate Substances (not considered in last review)
Substances included in last review but not prioritised owing to lacking information
Substances included in last review (and not prioritised) for which underpinning data has changed since last review

3. Monitoring-based Ranking
Proposed criteria for data acceptance of monitoring data;
Only substances monitored at least 4 MS in the same matrix?
90th percentile of monitored concentrations as opposed to mean concentrations (to try and account for seasonal variation)?
Criterion which establishes cases where the LOD is significantly above the screening PNEC or similar?

4. Modelling-based Ranking
Inclusion of metals and certain organo-metal substances
Possibly by use of a metal-specific, parallel modelling approach.
Such an approach would allow a combined ranking of both organic substances and metals based on the PEC/PNEC ratio.
REACH registration data is used to improve the quality of the exercise
All QSAR and other quantitative tools used in the previous prioritisation are reviewed to ensure fitness for purpose
Updates to the ECETOC TRA tool are appraised to determine if any would be useful to the process
PNEC values should be harmonised between approaches (monitoring and modelling)

5. Sources of Candidate Substances (for Modelling-based Ranking Exercise)
Substances added to PPP Directive Annex I since last review
Substances added to Biocides Directive Annex I since last review
REACH
Substances designated as SVHC since last review
Substances considered to be PBT or vPvB since the last review (and not designated as REACH SVHC)
High tonnage production substances and those with uses consistent with environmental release
Substances prioritised by MS as Specific Pollutants
Pharmaceuticals (pre-ranked based on risk?)
Substances for which modelling-based risk could not be assessed owing to a lack of data, or which were not prioritised but for which new underpinning information is now available.