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The factor V Leiden mutation: Spectrum of thrombotic events and laboratory evaluation  Franklin A. Bontempo, MD, Andrea Cortese Hassett, PhD, Hawazin Faruki,

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Presentation on theme: "The factor V Leiden mutation: Spectrum of thrombotic events and laboratory evaluation  Franklin A. Bontempo, MD, Andrea Cortese Hassett, PhD, Hawazin Faruki,"— Presentation transcript:

1 The factor V Leiden mutation: Spectrum of thrombotic events and laboratory evaluation 
Franklin A. Bontempo, MD, Andrea Cortese Hassett, PhD, Hawazin Faruki, DrPH, David L. Steed, MD, Marshall W. Webster, MD, Michel S. Makaroun, MD  Journal of Vascular Surgery  Volume 25, Issue 2, Pages (February 1997) DOI: /S (97) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Site of cleavage (arrow) of the 220bp segment of the normal and mutant factor V gene. Journal of Vascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Age distribution at diagnosis of 107 patients with factor V Leiden mutation and thrombotic events (entire column) and the 17 patients with myocardial infarction or stroke/transient ischemic attack (shaded part). Journal of Vascular Surgery  , DOI: ( /S (97) ) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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