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Myeloid Updates From the Summer Congresses
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Program Overview
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This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States and data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.
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Newly Diagnosed Acute Myeloid Leukemia
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Untreated AML The Current Landscape
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CPX-351 Phase 3 Trial Design
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CPX-351 vs 7 + 3 Older ND High-Risk AML
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CPX-351 Subset Analysis
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CPX-351 AEs
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CPX-351 Consolidation as Outpatient Therapy
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CPX-351 Subset Analysis
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FLT3-Mutated AML
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FLT3 Mutated AML CALGB 10603 Results
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Other FLT3 Inhibitors Crenolanib
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Crenolanib MRD Assessment
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Updates on Other Novel Agents Sorafenib
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New Approaches in TP53-Associated AML
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New Approaches in TP53-Associated AML HMAs
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Updates on Other Novel Agents Venetoclax Plus Low-Dose Cytarabine
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Updates on Other Novel Agents Venetoclax Plus HMAs
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Risk-Adapted Approach in AML GIMEMA, AML1310
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Risk-Adapted Approach in AML Results
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Key Takeaways
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Relapsed and Refractory Acute Myeloid Leukemia
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Overview
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IDH Mutations
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Novel Therapies in R/R AML Enasidenib
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Enasidenib Overall Efficacy
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Enasidenib Key Toxicities
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Novel Therapies in R/R AML Gilteritinib
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Gilteritinib Subset Analysis
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Novel Therapies in R/R AML Quizartinib
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Gene Testing in AML
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Myelodysplastic Syndromes
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MDS Treatment Higher-Risk Patients
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MDS Treatment Lower-Risk Patients
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Updates on Checkpoint Inhibitors Ipilimumab
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Updates on Checkpoint Inhibitors Ipilimumab Posttransplantation
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Updates on Checkpoint Inhibitors Nivolumab/Ipilimumab
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Updates on Other New Agents Rigosertib
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Updates on Other New Agents Vosaroxin
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Updates on Other New Agents Guadecitabine
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Key Takeaways
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Myeloproliferative Neoplasms
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Ruxolitinib vs BAT in Polycythemia Vera RESPONSE-2 Trial
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Long-Acting Interferon in PV PILOT-PV Trial
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PILOT-PV Trial Subset Analysis
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Novel JAK Inhibitors in MF: Momelotinib SIMPLIFY-1 Trial
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Novel JAK Inhibitors in MF: Momelotinib SIMPLIFY-2 Trial
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Novel JAK Inhibitors in MF: Pacritinib PERSIST-2 Trial
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PERSIST-2 Trial Subset Analysis
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Combination Therapy in MF AZA Plus RUX
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Abbreviations
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