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Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients  W. Zhang, G. Sun, S. Likhodii, M. Liu, E. Aref-Eshghi,

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Presentation on theme: "Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients  W. Zhang, G. Sun, S. Likhodii, M. Liu, E. Aref-Eshghi,"— Presentation transcript:

1 Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients  W. Zhang, G. Sun, S. Likhodii, M. Liu, E. Aref-Eshghi, P.E. Harper, G. Martin, A. Furey, R. Green, E. Randell, P. Rahman, G. Zhai  Osteoarthritis and Cartilage  Volume 24, Issue 5, Pages (May 2016) DOI: /j.joca Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Boxplots of six differential metabolites in the validation samples. P values were derived from the Kolmogorov–Smirnov test. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 ROC curve analysis results for six significantly differential metabolites. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Barcharts of expression of CTSB and CTSK in OA-affected and healthy cartilage. P values were derived from the Kolmogorov–Smirnov test. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions


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