1. Model Based Mediation With Domain Maps ___________________________
Guanrao Chen
William Sunna
Xiaosen Li
Instructor (Prof. Isabel Cruz)
The University of Illinois at Chicago

2. Different Schemes Our Goal ……. S1 S2 Sn
Federated Databases XML-Based Mediation Model-Based Mediation
One-World
One-/Multiple-Worlds
Complex Multiple-Worlds
Our Goal
Given different data sources:
And we have different queries: (Q1,Q2,……..Qk) over (S1,S2…..Sk)
Find answers to these questions: (A1,A2,……..Ak)
……. S1 S2 Sn

3. Model-based Mediation with Domain Map
User/Client
Domain Map
CM Integrated View
Integrated View Definition
IVD(S_1,S_2,…,S_k)
Mediator
GCM
GCM
GCM
CM S_1
CM S_2
CM S_k
CM Plug-ins
CM Queries & Results
CM Wrapper
CM Wrapper
CM Wrapper
XML Wrapper
XML Wrapper
XML Wrapper
S_1
S_2
S_k

4. ISIS Mediation Architecture MULTI-agent System Architecture
Interface
Agent
Query
Processing
Agent
Semantic
router
Agent CA
USER
Cooperation Bus CA CA
Ontology
Agent
Wrapper
Agent
Wrapper
Agent
CA = Cooperation agent S1 S2

5. Problem Definition Project:
Integration of Two Separate Biology Databases to process queries that require the knowledge of both.
1. Neuron Image Database(NCMIR)
The National Center for Microscopy and Imaging Research (NCMIR) is a federally funded research facility dedicated to advancing three-dimensional microscopy and imaging of biological materials. (
2. Neuron Receptor Database (SenseLab)
The SenseLab Project is a 10-year effort by an international network of researchers to develop a comprehensive approach to building integrated, multidisciplinary models of neurons and neural systems, using the olfactory pathway as a model. (

6. Example Query/Result Deliverables: answer to the User’s Queries.
Does hippocampus CA1 pyramidal cell has glutamate receptor and what the effect on the neuron shape caused by the Ca++ ion entered through the glutamate receptor during LTP?
Query/Result
SYSTEM THAT CAN PROCESS THE QUERY
FROM MULTIPLE COMPLEX WORLD
DATABASES
Deliverables: answer to the User’s Queries.
Example: for queries above, the answer is:
Yes / Neuron Image-Ids before and after LTP

7. Project Plan Deliverables
Apply Model-based Mediation with Domain Map to to solve the problem
Adapt available software to realize some of the subsystems, e.g., XML-Wrapper
Try to implement a CM-Wrapper
Use RDF or XML Schema with F-logic as a GCM
Use expert knowledge to construct the domain map
Use Description Logic to formalize the domain map
Deliverables
A detailed written project report that describes the design and the implementation of the solution to the problem
Presentation of the design and the implementation