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Double Jeopardy: Autoimmune Myelofibrosis with Pyoderma Gangrenosum

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Presentation on theme: "Double Jeopardy: Autoimmune Myelofibrosis with Pyoderma Gangrenosum"— Presentation transcript:

1 Double Jeopardy: Autoimmune Myelofibrosis with Pyoderma Gangrenosum
Cole Sterling, BS, Genevieve M. Crane, MD, PhD, Jihad Al-hariri, MD, Satish Shanbhag, MBBS, MPH  The American Journal of Medicine  Volume 130, Issue 1, Pages e1-e4 (January 2017) DOI: /j.amjmed Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Bone marrow biopsy showing increased reticulin fibrosis: hematoxylin and eosin (H&E) ×100 (A), H&E ×200 (B), and reticulin ×200 (C). Peripheral blood smear showing anisopoikilocytosis and occasional teardrop cells (D). The American Journal of Medicine  , e1-e4DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Figure 2 Right inframammary (A) and right inguinal wounds (B) on admission and 3 days later (C,D). The American Journal of Medicine  , e1-e4DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions

4 Figure 3 Right inframammary (A) and right inguinal wounds (B) after 18 weeks of steroids and intravenous immunoglobulin. Repeat bone marrow biopsy showing a rare focus of residual fibrosis adjacent to an area of normal marrow (C) with near complete resolution of the prior reticulin fibrosis (D): hematoxylin and eosin ×200 (C), and reticulin ×200 (D). The American Journal of Medicine  , e1-e4DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions


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