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Individualized Dosing and Therapeutic Drug Monitoring (TDM) of ATG is Feasible, Safe, Effective, and Associated with Excellent Immune Reconstitution 

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Presentation on theme: "Individualized Dosing and Therapeutic Drug Monitoring (TDM) of ATG is Feasible, Safe, Effective, and Associated with Excellent Immune Reconstitution "— Presentation transcript:

1 Individualized Dosing and Therapeutic Drug Monitoring (TDM) of ATG is Feasible, Safe, Effective, and Associated with Excellent Immune Reconstitution  Caroline A. Lindemans, Rick Admiraal, Colin G. Haar, Lysette E.J. Ebskamp van Raaij, Amelia M. Lacna, Marc Bierings, Stefan Nierkens, Jaap-Jan Boelens  Biology of Blood and Marrow Transplantation  Volume 23, Issue 3, Pages S124-S125 (March 2017) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 (A) Calculated (left panel) and actual (right panel) ATG exposure of a representative patient. In the left, solid line indicates median calculated exposure; dotted lines: 95% confidence interval of calculated exposure. On the right, the dots are actual measured concentrations, the line represents actual exposure. The median calculated concentration-time profile matches well with the actual concentration-time profile. (B) CD4+ T cell counts of 6 evaluable patients after HCT. Biology of Blood and Marrow Transplantation  , S124-S125DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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