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Astrid Petersen, Ph. D. , Ursula Bentin-Ley, Ph. D. , Vibeke Ravn, Dr

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Presentation on theme: "Astrid Petersen, Ph. D. , Ursula Bentin-Ley, Ph. D. , Vibeke Ravn, Dr"— Presentation transcript:

1 The antiprogesterone Org 31710 inhibits human blastocyst-endometrial interactions in vitro 
Astrid Petersen, Ph.D., Ursula Bentin-Ley, Ph.D., Vibeke Ravn, Dr.Med.Sci., Klaus Qvortrup, Ph.D., Steen Sørensen, Dr.Med.Sci., Henrik Islin, Ph.D., Anita Sjögren, Lic.Med.Vet., Sietse Mosselmann, Ph.D., Lars Hamberger, Ph.D.  Fertility and Sterility  Volume 83, Issue 4, Pages (April 2005) DOI: /j.fertnstert Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Scanning electron micrograph of cultured human endometrial epithelial cells (control culture) demonstrating cells with swollen microvilli (arrows and frame) and developing pinopodes (P). Bar: 20 μm. Inset: Higher magnification of framed area in main panel. The apical surface of an endometrial epithelial cell is covered with dense (M) and swollen (vertical arrows) microvilli and also displays long and slender cilia (horizontal arrow). Bar: 5 μm. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Scanning electron micrograph of a human blastocyst that attached to a wrinkled area on the cell culture. At the attachment site, pronounced pinopode formation was present (arrow), whereas other areas of the culture did not display pinopodes. (Bar: 100 μm.) Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Scanning electron micrograph of a human blastocyst attached to an endometrial cell culture with few pinopodes present. (Bar: 100 μm.) Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions


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