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Recurrent Pancreatitis, Rash, and Diarrhea: Crohn's Disease

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Presentation on theme: "Recurrent Pancreatitis, Rash, and Diarrhea: Crohn's Disease"— Presentation transcript:

1 Recurrent Pancreatitis, Rash, and Diarrhea: Crohn's Disease
Martin H. Gregory, BA, Alex Henderson, BA, Kelsey Klostermeyer, BA, Mohammad Esmadi, MD, Mohamed Yousef, MD, David Ewing, MD, Kara M. Braudis, MD, Natraj Katta, MD  The American Journal of Medicine  Volume 128, Issue 2, Pages (February 2015) DOI: /j.amjmed Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Tender erythematous lesions developed on the night of admission. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions

3 Figure 2 (A) Photomicrographs of the patient's skin biopsy findings showed lobular panniculitis with prominent ghost cells and a dense neutrophilic infiltrate accompanied by hemorrhage (hematoxylin and eosin stain, 20×). (B) Anucleate amorphous ghost cells had areas of basophilic stippling secondary to calcification (hematoxylin and eosin, 40×). (C) Enzymatic fat necrosis with a heavy neutrophilic infiltrate was evident (hematoxylin and eosin, 200×.) The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions

4 Figure 3 (A) Photomicrographs depicted the patient's colon biopsy findings. A right colon biopsy demonstrated chronic colitis with crypt architectural disarray, glandular atrophy, and reactive epithelial changes (hematoxylin and eosin, 100×). (B) A left colon biopsy showed active cryptitis with multiple crypt abscesses (hematoxylin and eosin, 200×). Noncaseating granulomas that are pathognomonic for Crohn's disease were not seen, but these are infrequently found. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions


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