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Reactivation of occult herpes simplex meningoencephalitis after temporal lobe resection for refractory epilepsy – A case report  Einar Osland Vik-Mo,

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Presentation on theme: "Reactivation of occult herpes simplex meningoencephalitis after temporal lobe resection for refractory epilepsy – A case report  Einar Osland Vik-Mo,"— Presentation transcript:

1 Reactivation of occult herpes simplex meningoencephalitis after temporal lobe resection for refractory epilepsy – A case report  Einar Osland Vik-Mo, Bård K. Krossnes, Milo Stanisic, Arild Egge, Ellen Holter, Erik Taubøll, Kjell Heuser, Christian G. Lund  Seizure - European Journal of Epilepsy  Volume 23, Issue 4, Pages (April 2014) DOI: /j.seizure Copyright © 2014 British Epilepsy Association Terms and Conditions

2 Fig. 1 (A) FDG-PET CT cerebrum scans reduced metabolism in the left hippocampus (arrow). (B) FLAIR MRI showing reduced volume of the left hippocampus (arrow). (C) CT cerebrum scan showing cerebral parenchymal microcalcifications in the frontal and parietal lobes (arrows). (D) T2 cerebral MRI showing left temporal and frontal edema characteristic for HSE. (E) Overview histological images showing small clusters of CD3-positive lymphocytes in hippocampus. (F) Hematoxylin–eosin staining consistent with lymphocyte infiltration, confirmed with CD3-positive staining for T-lymphocytes (G). Some CD68-positive microglia were found among the lymphocytes (H). Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2014 British Epilepsy Association Terms and Conditions


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