1. Two-year prospective, randomized trial comparing an innovative twice-a-week progestin regimen with a continuous combined regimen as postmenopausal hormone therapy 
Antonio Cano, M.D., Juan J Tarı́n, Ph.D., José Luis Dueñas, M.D. 
Fertility and Sterility 
Volume 71, Issue 1, Pages (January 1999)
DOI: /S (98)

2. FIGURE 1
Percentage of women receiving intermittent or continuous progestin doses each month who recorded spotting (A) or bleeding (B). Open circles and interrupted line = intermittent dosing regimen; closed circles and continuous line = continuous dosing regimen.
Fertility and Sterility  , DOI: ( /S (98) )

3. FIGURE 2
Regression lines of the proportion of women (p) with spotting (A) or bleeding (B) at time (x) of treatment with intermittent or continuous progestin doses according to the following model: probit (p) = intercept + B (x). (A), The bottom line, with the sharper slope, corresponds with the intermittent progestin dosing protocol. Pearson goodness-of-fit: P>.05. Parallelism test: P≤.01. Equations for the regression lines: y = 4.51 − x (intermittent dosing regimen), and y = 4.35 − x (continuous dosing regimen). (B), The bottom line corresponds with the intermittent progestin dosing protocol. Pearson goodness-of-fit: P>.05. Parallelism test: P≤1.00. Equations for the regression lines: y = 3.90 − x (intermittent dosing regimen), and y = 3.95 − x (continuous dosing regimen). Open circles = intermittent dosing regimen; closed circles = continuous dosing regimen.
Fertility and Sterility  , DOI: ( /S (98) )

4. FIGURE 3
Evolution of endometrial thickness (mean ± SEM) for the intermittent and continuous progestin dosing groups during the study, as evaluated by vaginal ultrasound. Open bar = intermittent dosing regimen; striped bar = continuous dosing regimen.
Fertility and Sterility  , DOI: ( /S (98) )

5. FIGURE 4
Concentrations of lipids and lipoproteins (means ± SEM) for the intermittent (A) and continuous (B) progestin dosing groups at baseline and at each 6-month visit. At each time point: open bar = cholesterol; striped bar = triglycerides; cross-hatched bar = HDL-C; stippled bar = LDL-C.
Fertility and Sterility  , DOI: ( /S (98) )