1. Bottom Line
Diagnostic reproducibility in the range of intraductal proliferative lesions is poor
Even amongst breast pathology experts
Even when specific criteria are used
Particularly in the ADH/limited LG-DCIS realm
Significance on the core of ADH vs DCIS has fewer management implications than UDH vs ADH.
Still rely heavily on morphology alone.
Deepers, IHC can sometimes help.
So if in doubt, send it out! Or share.
Sometimes reassuring just to have another pair of eyes on it. I have the luxery of being able to walk down the hall to someone’s office. Not everyone has that, but helpful to share it around.

2. Post-quiz
Classic images from the textbooks.

3. 1.
UDH

4. 2.
ADH
0.1 cm

5. 3.
ADH

6. 4.
UDH

7. 5.
FEA

8. 6.
CCC

9. UDH

10. Answers Pre-quiz Post-quiz 1. UDH 2. ADH 3. DCIS 4. FEA 5. UDH
1. UDH 2. ADH 3. ADH 4. UDH 5. FEA 6. CCC