1. Chapter 21: Drugs for Hypertension
DISCUSSION POINTS
Chapter 21: Drugs for Hypertension
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

2. Failure to control Hypertension
- damages small blood vessels, leading to accelerated narrowing of arteries, resulting in angina, myocardial infarction, and peripheral vascular disease
- heart failure
- transient ischemic attacks
(continued)
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

3. Failure to control Hypertension
- cerebral vascular accidents or strokes
- renal damage
- retinal damage
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

4. Three Primary Factors for Blood Pressure - cardiac output
- peripheral resistance
- blood volume
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

5. Normal Regulation of Blood Pressure - vasomotor center - baroreceptors
- chemoreceptors
- emotions and hormones
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

6. Five Primary Classes of Drugs Used to Treat Hypertension - Diuretics
- Calcium channel blockers
- Agents blocking the renin-angiotensin pathway
- Adrenergic agents
- Direct-acting vasodilators
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr.
Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.