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Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients

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Presentation on theme: "Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients"— Presentation transcript:

1 Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients
Simon A. Joosse, Klaus Pantel  Cancer Cell  Volume 28, Issue 5, Pages (November 2015) DOI: /j.ccell Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Sources of Liquid Biopsy
Blood can be separated into different fractions in order to enrich for tumor-associated biomarkers. From the mononuclear cell fraction, circulating tumor cells (CTCs) may provide genomic, transcriptomic, and proteomic information on the tumor. From plasma or serum, cell-free nucleotides and exosomes can be further used to interrogate cancer-secreted bioparticles. Tumor educated platelets (TEPs) carry additional information on the location of the tumor in their mRNA. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2015 Elsevier Inc. Terms and Conditions


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