1. Spermatozoa from infertile patients exhibit differences of DNA methylation associated with spermatogenesis-related processes: an array-based analysis 
Cristina Camprubí, Albert Salas-Huetos, Riccardo Aiese-Cigliano, Anna Godo, Maria-Carme Pons, Giancarlo Castellano, Mark Grossmann, Walter Sanseverino, José I. Martin-Subero, Nicolás Garrido, Joan Blanco 
Reproductive BioMedicine Online 
Volume 33, Issue 6, Pages (December 2016)
DOI: /j.rbmo
Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

2. Figure 1 Flow chart summarizing the statistical analyses performed.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

3. Figure 2
Heatmap displaying the methylation status of the 16,955 CpG with a coefficient of variation greater than The horizontal bar above the heatmap shows the two main clusters: cluster 1 in red and cluster 2 in blue. Each column of the heatmap represents a single sample indicated at the bottom. Each cell of each line of the heatmap represents the methylation level for each CpG. Methylation levels are indicated in the colour scale on the right side of the figure as dark blue (0.0) to dark red (1.0).
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

4. Figure 3
DM-CpG methylation profiles according to chromosome state, gene annotation and CpG class. TSS = transcription start site, Txn = related to transcriptional processes.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

5. Figure 4
Heatmap displaying the methylation status of the 76 DM-CpG within the 17 DM-loci. The horizontal bar above the heatmap indicates the control (light grey) and infertile (dark grey) population. Each column of the heatmap represents a single sample indicated at the bottom. Each cell of each line of the heatmap represents the methylation level for each DM-CpG and gene (indicated on the right side of the heatmap). Methylation levels are indicated in the colour scale on the left side of the figure as dark blue (0.0) to dark red (1.0).
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions