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Leptomeningeal Infiltration, the Hallmark of Neurosarcoidosis

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1 Leptomeningeal Infiltration, the Hallmark of Neurosarcoidosis
Hafid Ait-Oufella, MD, PhD, Caroline Gabignon, MD, Jean Capron, MD, Arsene Mekinian, MD, PhD  The American Journal of Medicine  Volume 130, Issue 8, Pages e331-e332 (August 2017) DOI: /j.amjmed Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure Brain computed tomography showing bifrontal hypodensity (A; white arrows, precontrast) with focal meningeal enhancement (B; white arrows, postcontrast). Brain magnetic resonance imaging confirmed marked bifrontal edema (C; white arrows, hyperintense on axial T2-weighted image) and leptomeningeal thickening (D; white arrows, axial T1-weighted image with contrast). Salivary gland histopathology showing typical noncaseating granuloma with giant cells (E; black arrows, hematoxylin staining, ×10 magnification). The American Journal of Medicine  , e331-e332DOI: ( /j.amjmed ) Copyright © 2017 Elsevier Inc. Terms and Conditions


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